What does her2 positive and hormone receptor positive mean Meaning and Definition
What does her2 positive and hormone receptor positive mean
Pronunciation
/hwɑt ˈhɛr tuː pɒzɪtɪv ænd hɔrmoʊn riˈsɛptər pɒzɪtɪv miːn/
Part of Speech
Phrase
Definition
A medical term used to describe breast cancer that tests positive for HER2 (human epidermal growth factor receptor 2) and hormone receptors, indicating that the cancer growth is driven by the hormone estrogen and/or progesterone.
Examples
- The doctor explained that the breast cancer was HER2 positive and hormone receptor positive, and outlined the treatment options.
- The patient was relieved to learn that her cancer was HER2 positive and hormone receptor positive, as it responded well to targeted therapy.
Synonyms
- HER2+ HR+
- Hormone-sensitive breast cancer
Antonyms
- HER2 negative
- Hormone receptor negative
Additional Information
Breast cancer that is HER2 positive and hormone receptor positive tends to grow more rapidly and aggressively than other types of breast cancer. However, targeted therapies such as trastuzumab and pertuzumab have been developed to specifically target HER2-positive cells, and hormone therapies such as tamoxifen and aromatase inhibitors can help block the growth of hormone-sensitive cells.
Early detection and treatment are crucial for improving outcomes in patients with HER2-positive and hormone receptor-positive breast cancer.
Research is ongoing to develop more effective treatments and improve understanding of the molecular mechanisms underlying this type of breast cancer.
Eymology
The term “HER2 positive and hormone receptor positive” is derived from the names of the two proteins involved: HER2 (human epidermal growth factor receptor 2) and hormone receptors (estrogen and progesterone receptors).
Usage Notes
This term is primarily used in medical contexts, particularly in oncology and breast cancer research.
Cultural References
Breast cancer awareness campaigns often feature stories of women diagnosed with HER2-positive and hormone receptor-positive breast cancer, highlighting the importance of early detection and treatment.
Idiomatic Expressions or Phrases
- Her2 status
- Hormone receptor status
Related Words or Phrases
- Breast cancer subtype
- Tumor marker
Collocations
- HER2-positive breast cancer
- Hormone receptor-positive tumors
Frequency of Use
This term is frequently used in medical journals and breast cancer research publications.
Common Misspellings
- Her 2 positive and hormone receptor positive
- HER2 pos and HR pos